Some Features of TYPE-C™ Columns: Chromatographer’s Benefits
Silicon-Carbon Bonds instead of Siloxane	More stable and durable. UDC-Cholesterol: pH 2.0 – 8.2 Bidentate C18: pH 1.5 – 10.0+ Bidentate C8: pH 1.5 – 10.0+
Si-H replaces Si-OH	Rapid equilibration between gradients
Temperature Stability Increased	Use Temperature as a selectivity Tool
Can be used with Hard Lewis Acids	Use Lewis Acids as Mobile Phase Additives
Free of Salts	Contaminant Free Surface
Bonded to a Silicon-Hydride Surface	Will not strongly bind Carboxylic Acids or Sulfonic Acids Minimized Silanophilic Activity Stable at high flow rates (up to 3ml/minute)
Weakly Associated Hydration Shell	Water Friendly Columns, easy to use. Very rapidly remove water from the stationary phase and silica.
Use 100% water on C18	Without loss of retention with time
Lack of pH hysteresis	Quickly change mobile phases and pH buffers.
Perform ANP & RP at the same time	Separate Polar & Non-Polar compounds in the same run
Retain Polar compounds at extremely high organic content	Increases sensitivity of mass detectors using ESI
User Non-Polar solvents	Retain & separate compounds which are non-soluble in water
Low affinity for water	Run normal phase separations on these "Bonded" columns without the hassles of moisture in solvents
Use high organic % content in mobile phases	Shorten sample prep time. No need to dry down samples after SPE. Inject sample diluent (high organic) right on the column
Bonded phase that performs ANP & RP & ONP	Get the performance of HILIC columns on a stable, robust bonded phase
High efficiency & stable	Great peak shapes & columns that last a long time