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About TYPE-C Silica based HPLC products?
What are they and how do they help Chromatographers?
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Introducing TYPE-C Silica
Think Inside the Box... Solve difficult separation problems with your current skill set and experience.
TYPE-C silica based HPLC columns have opened a new chapter in the book that describes chromatographic supports
and phases. Based on high purity-low metal content Type-B silica, the manufacturing process for TYPE-C Silica
continues where others leave off. Our process produces a surface populated with silicon-hydride groups (Si-H) which
are very stable and non polar.
The TYPE-C Silica support still has all the advantages of Type-B silica such as spherical shape, low metal
content, high purity, high mechanical strength, narrow pore size distribution, wide range of pore sizes, easily
chemically modified, no swelling in the presence of solvents for stable packed beds and does not produce fines as
irregular silica. TYPE-C Silica products also have many advantages over the ordinary Type-B columns on the market.
Among them is that they can be used for 3 different modes of HPLC and sometimes two at the same time. This gives
you an enormous selectivity power. On one column you can separate polar and non polar compounds at the same time or
in different runs. One column can be used for classic reverse phase, normal phase with non polar solvents such as
hexane and can be used for normal phase elution with aqueous solvents. This is called Aqueous Normal Phase.
Other benefits are the incredible speed between gradient runs that can be used to equilibrate or clean your column
from matrix effects. For normal runs, less than one minute is needed.
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