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Cogent F5 header
Cogent F5™ HPLC Columns are designed to provide a unique separation mechanism for a wide range of molecules but are particularly effective for retention of fluorinated compounds. CogentF5™ is very useful to differentiate between halogen bearing compounds and their analogs and positional isomers.

Use with a Wide Range of Solvents
Using an Acetonitrile and Water mobile phase, aromatic compounds (commonly found in pharmaceuticals) are easily separated. When used with fluorinated solvents such as 2,2,2-trifluoroethanol, a very useful selectivity for compounds will be observed for hydrogen bonding/donor functionalities. Using Trifluoracetic acid at low pH can be effective for peptide and other biological separations.

Useful for a Wide Range of Compounds
An increased retention may be found compared with Phenyl, C8, C18 or other alkyl based columns and may initiate reversal in retention order in natural products such as Taxol™ or taxanes, as well as with




  Natural Products Purification
  Unique Selectivity
  Useful for Aromatics
  Improved Phenyl Phase

F5 illustration Structure of Stationary Phase

 
Specifications
Carbon Load:  16%
Particle Size:
Pore Size: 60A

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