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Inline Degasser

Frequently Asked Questions for Standard 4 Channel Inline Degasser for HPLC Mobile Phase

  1. If I do not degas my mobile phase, what are the consequences?


  2. What is the internal volume of the Standard 4 Channel Inline Degasser?


  3. What is the degassing membrane made from?


  4. Is there a minimum or maximum number of channels I can use with the Standard 4 Channel Inline Degasser?


  5. I am afraid to use electric devices with HPLC solvents. What if they leak, will I have a “spill incident”?


  6. I have an inline degasser from another supplier and my HPLC solvents kept breaking down. How will your Standard 4 Channel Inline Degasser be different?


  7. What does the Digital Display actually tell me while it is operating?


  8. What is the variation of the vacuum during operation and how does this unit control it?


  9. Can I “Double Degas” my mobile phase with the Standard 4 Channel Inline Degasser?


  10. Can I use an inline filter with the Standard 4 Channel Inline Degassers?


  11. Will I begin to evaporate my organic solvents in the Standard 4 Channel Inline Degasser?


  12. What happens to the gasses that are removed from the Inline Degasser?


  13. What is the warranty period of the Standard 4 Channel Inline Degasser?


  14. Is the Standard 4 Channel Inline Degasser CE Marked?


  15. Are higher flow rate models available then the Standard 4 Channel Inline Degasser?


  16. Is there a minimum flow rate for the Standard 4 Channel Inline Degasser?


  17. Is there a temperature maximum or minimum for the Standard 4 Channel Inline Degasser?


  18. Is there any preventative maintenance that is required with the Standard 4 Channel Inline Degasser?


  19. I have heard that some degassers will add to baseline noise. Will the TG-14 create noise in my baseline?

1. If I do not degas my mobile phase, what are the consequences? [top]
Solvents that are exposed to the atmosphere have the ability to absorb compressible CO2 and Oxygen. When your HPLC has low back pressure, the actual linear flow of materials could be different then when you have higher back pressure. This is due to the compressibility of air v. the compressibility of gas. This means that your HPLC results could different retention times and different peak shapes.

Also, Noisy baselines occur which can lead to very unreliable results in both quantitation and retention times. Some columns, most notably polymeric columns, do not tolerate outgassing very well.

2. What is the internal volume of the Standard 4 Channel Inline Degasser? [top]
The internal volume is less than 0.486ml.

3. What is the degassing membrane made from? [top]
The degassing membrane is made from Polymer V, the most appropriate degassing membrane available today for HPLC mobile phases. Polymer V is much more gas permeable then PTFE.

4. Is there a minimum or maximum number of channels I can use with the Standard 4 Channel Inline Degasser? [top]
No, not at all. In fact, when you use less than four channels at the same time, the other 3 automatically use their shut off valves. The flow rate and impact on output is affected. The more channels, the more the output.

5. I am afraid to use electric devices with HPLC solvents. What if they leak, will I have a “spill incident”? [top]
No, the Standard 4 Channel Inline Degasser is Equipped with a leak sensor, should a solvent leak occur, the vacuum pump is immediately stopped. Also, the Degasser is supplied with a 5V signal that you can plug into an intelligent pump that will stop the pump in the event of a leak or other system failure.

6. I have an inline degasser from another supplier and my HPLC solvents kept breaking down. How will your Standard 4 Channel Inline Degasser be different? [top]
The use of a Teflon elastomer for the vacuum seal has eliminated solvent decomposition problems.

7. What does the Digital Display actually tell me while it is operating? [top]
The actual vacuum is directly measured in the vacuum chamber and is displayed in real time. This is extremely helpful and gives you feedback and tells you that your mobile phase is being degassed properly.

Error Codes: Er 1... This error code indicates the motor failure. This appears on the LCD display when the motor fails to activate after three attempts. The Degasser will shut down automatically.
Er 2... The error code indicates the degassing failure. This appears on the LCD display when the vacuum chamber fails to reach the proper pressure level. The Degasser will shut down automatically.
Er 3... This error code indicates irregularity in power voltage. This appears on the LCD display when the AC adapter fails and results in voltage irregularity.

8. What is the variation of the vacuum during operation and how does this unit control it? [top]
A high-vacuum-generating vacuum pump combined with a CPU controls the vacuum level by intervals of 2hPa.

9. Can I “Double Degas” my mobile phase with the Standard 4 Channel Inline Degasser? [top]
Yes, absolutely. Simple take the outlet of the Degasser from one channel and reroute it into another channel. You will subject the mobile phase to twice the degassing and have twice the opportunity to remove all gases.

10. Can I use an inline filter with the Standard 4 Channel Inline Degassers? [top]
Yes, you can. Put the inline filter on the high pressure side of your pump.

11. Will I begin to evaporate my organic solvents in the Standard 4 Channel Inline Degasser? [top]
No, the maximum vacuum your mobile phase will ever be subjected to is 100 Torr for a relatively short period of time. Under these conditions, organic solvents used for HPLC will not pass through the degassing membrane.

12. What happens to the gasses that are removed from the Inline Degasser? [top]
Every 8 hours, the Degasser will “exhaust” the gases from the vent on the back of the unit. This is and the operator is not involved in this process.

13. What is the warranty period of the Standard 4 Channel Inline Degasser? [top]
One year parts and labor.

14. Is the Standard 4 Channel Inline Degasser CE Marked? [top]
Yes.

15. Are higher flow rate models available then the Standard 4 Channel Inline Degasser? [top]
Yes, if you are interested in a unit that can handle more than 5ml/minute, please contact our Customer Service department or call us at 1-732-578-1777.

16. Is there a minimum flow rate for the Standard 4 Channel Inline Degasser? [top]
No.

17. Is there a temperature maximum or minimum for the Standard 4 Channel Inline Degasser? [top]
No, within reason. The units will operate under the same temperature conditions as a typical HPLC column or instrument.

18. Is there any preventative maintenance that is required with the Standard 4 Channel Inline Degasser? [top]
No.

19. I have heard that some degassers will actually add to the baseline noise. Will the TG-14 create noise in my baseline? [top]
The TG-14 will not add any noise to your baseline. However, regarding the noise issue for other degassers, some degassers have a very wide vacuum range (150-200 Torr) and this wide tolerance can leave some solvents degassed at different levels. This could be noticeable on a baseline at high sensitivity. Our tight control of the vacuum level means consistent degassing regardless of solvent and no noise will be added to the baseline.

 

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