Buffer Additives for HPCE

Additive	Function
Organic Solvents	Modify EOF Solubilize Sample Matrix Improve Selectivity
Urea	Solubilize Proteins Denature oligonucleotides
Surfactants	MECC, Separation of neutral Species Charge reversal of Capillary Wall
Cellulose Derivatives	Reduce EOF Sieving Mechanism
Cyclodextrins	Separation of Positional Isomers or enantiomers